YAP1 Takes Over when Oncogenic K-Ras Slumbers
نویسنده
چکیده
It is of great therapeutic importance to understand why tumors relapse after the failure of therapies targeting oncogenes to which cancer cells are addicted. In this issue, Kapoor et al. and Shao et al. identify the transcriptional coactivator YAP1 as a central driver of compensation for the loss of K-Ras signaling in K-Ras-dependent cancers.
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ورودعنوان ژورنال:
- Cell
دوره 158 شماره
صفحات -
تاریخ انتشار 2014